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Procedure: Endoscopic dilation of subglottic stenosis Procedure: Endoscopic resection of the stenosis Procedure: Tracheal Resection Detailed Description: Idiopathic subglottic stenosis iSGS is a rare charung in which the trachea narrows for no known reason. Although uncommon with an estimated incidence ofpersons per yearboth the disease and its therapies profoundly affect patients' ability to breathe, communicate and swallow. Breathing difficulties i. However, patients can also experience debilitating voice changes and swallowing problems due to the onlinf or its treatment. Onlline with this disease often require several surgeries per year. A variety of treatments have been advanced to manage iSGS but are generally categorized into: 1 endoscopic dilation of the tracheal stenosis accomplished with rigid instruments or inflatable balloons ; 2 endoscopic resection of the stenosis with prolonged medical therapy after surgery ; or 3 open neck surgery with resection of the affected tracheal segment with end-to-end anastomosis.

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All approaches have unique and often disabling associated side effects, which can ificantly affect a patient's quality of life. Because the disease is rare, it is difficult for patients to find good information so that they can understand the spectrum of treatment options. This is particularly difficult because most patients present with severe breathing trouble and need treatment quickly, limiting their ability to explore options. Additionally, there is a general lack of high-quality, reliable, and accessible data to inform individual patient decision-making.

Imperfect information and limited evidence on treatment outcomes complicate patient decision-making as they try to balance survival, symptoms, and quality of life considerations. Beyond the gaps in understanding the relative effectiveness of the different treatments charinb, no studies have explored functional outcomes in iSGS i.

These endpoints are important to patients and are arguably a primary determinant in decision-making. Direct engagement with patients is critical to understand these quality of life considerations, since patient and physician perspectives aren't always the same.

For example, show that endoscopic dilation is associated with a higher rate of disease recurrence and thus need for repeated surgery. Each patient can require repeated surgeries to keep their trachea open, which increases odds of treatment side effects and complications. All approaches have unique and often disabling associated side effects, which can ificantly affect a patient's quality of life.

Because the disease is rare, it is difficult for patients to find good information so that they can understand the spectrum of treatment options. This is particularly difficult because most patients present with severe breathing trouble and need treatment quickly, limiting their ability to explore options. Additionally, there is a charring lack of high-quality, reliable, and accessible data to inform individual patient decision-making.

Imperfect information and limited evidence on treatment outcomes complicate patient decision-making as they try to balance survival, symptoms, and quality of life considerations. Beyond the gaps in understanding the relative effectiveness of the different treatments available, no studies have explored functional outcomes in iSGS i. These endpoints are important to patients and are arguably a primary determinant in decision-making.

Direct engagement with patients is critical to understand these quality of life considerations, since patient and physician perspectives aren't always the same.